Sam50 Monoclonal antibody, PBS Only

Sam50 Monoclonal Antibody for IF/ICC, ELISA
Cat No. 67425-1-PBS
Clone No.2H6H9

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

IF/ICC, ELISA

SAMM50, SAMM 50, OMP85, CGI-51, CGI 51

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

67425-1-PBS targets Sam50 in IF/ICC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Sam50 fusion protein Ag15155 Predict reactive species
Full Name sorting and assembly machinery component 50 homolog (S. cerevisiae)
Calculated Molecular Weight 469 aa, 52 kDa
Observed Molecular Weight 52 kDa
GenBank Accession NumberBC007830
Gene Symbol Sam50
Gene ID (NCBI) 25813
RRIDAB_2882664
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9Y512
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Sam50, encoded by the SAMM50 gene, is an essential protein of the mitochondrial outer membrane (OMM). It contains a beta-barrel domain conserved from bacteria to man (PMID: 14570913). Sam50 is a part of the sorting and assembly machinery (SAM) necessary for the assembly of beta-barrel proteins in the OMM (PMID: 22252321). It is crucial for maintaining mitochondrial shape, morphology of mitochondrial cristae, and assembly of the mitochondrial respiratory chain complexes (PMID: 26587038; 22252321; 25781180). Polymorphisms in the SAMM50 gene have been associated with development and progression of nonalcoholic fatty liver disease (PMID: 23535911).

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