SOS1 Recombinant antibody, PBS Only

SOS1 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2J16

Cat no : 82784-2-PBS

Synonyms

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Validation Data Gallery

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  WB analysis using 82784-2-RR (same clone as 82784-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82784-2-RR (SOS1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82784-2-PBS in a different storage buffer formulation.

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Product Information

82784-2-PBS targets SOS1 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Peptide
• Full Name: son of sevenless homolog 1 (Drosophila)
• Calculated Molecular Weight: 152 kDa
• Observed Molecular Weight: 170 kDa
• GenBank Accession Number: NM_005633
• Gene Symbol: SOS1
• Gene ID (NCBI): 6654
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

SOS1 promotes the exchange of Ras-bound GDP by GTP. EPS8, E3B1 and SOS1 form a tricomplex in vivo that exhibits RAC-specific guanine nucleotide exchange factor activity in vitro. Defects in SOS1 are the cause of gingival fibromatosis 1 (GGF1). Defects in SOS1 are the cause of Noonan syndrome type 4 (NS4). The antibody is specific to SOS1.