SON Recombinant antibody, PBS Only

SON Uni-rAbTM Recombinant Antibody for WB, IF/ICC, FC (Intra), ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, FC (Intra), ELISA

Conjugate

Unconjugated

CloneNo.

240845B7

Cat no : 83787-5-PBS

Synonyms

SON DNA binding protein, KIAA1019, HSPC312, DBP5, C21orf50



Product Information

The immunogen of 83787-5-PBS is SON Fusion Protein expressed in E. coli.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen SON fusion protein Ag27620
Full Name SON DNA binding protein
Calculated Molecular Weight 264 aa
Observed Molecular Weight 250-300 kDa
GenBank Accession NumberNM_001291411
Gene Symbol SON
Gene ID (NCBI) 6651
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

SON, also called C21orf50 and DBP5, is a nuclear speckle-localized protein that shares homology with pre-mRNA splicing accessory factors (PMID: 10950926). It is an RNA-binding protein that acts as an mRNA splicing cofactor by promoting efficient splicing of transcripts that possess weak splice sites, and specifically promotes splicing of many cell-cycle and DNA-repair transcripts that possess weak splice sites, such as TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A, and FANCG (PMID: 20581448; 21504830).