SNAT2 Recombinant antibody, PBS Only

SNAT2 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241059C6

Cat no : 83968-5-PBS

Synonyms

SLC38A2, Protein 40-9-1, Protein 40 9 1, PRO1068, KIAA1382

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Validation Data Gallery

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  WB analysis using 83968-5-RR (same clone as 83968-5-PBS)

  Boiled and unboiled mouse brain tissues were subjected to SDS PAGE followed by western blot with 83968-5-RR (SLC38A2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83968-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83968-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83968-5-RR against Human SNAT2 were performed. The affinity constant is below 1 pM.

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Product Information

The immunogen of 83968-5-PBS is SNAT2 Fusion Protein expressed in E. coli.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: SNAT2 fusion protein Ag23082
• Full Name: solute carrier family 38, member 2
• Observed Molecular Weight: 56 kDa
• GenBank Accession Number: BC040342
• Gene Symbol: SLC38A2
• Gene ID (NCBI): 54407
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

SNAT2 (Sodium-dependent neutral amino acid transporter-2), the ubiquitous member of SLC38 family, accounts for the activity of transport system A for neutral amino acids in most mammalian tissues (PMID: 16734764). SNAT2 mediates uptake of neutral α-amino acids and are expressed in central neurons (PMID: 19240036). SNAT2 is expressed in breast cancer cell lines. SLC38A2 also acts as a selective target for inhibiting growth of Gln-dependent breast cancer cell lines (PMID: 33028955).