SMYD4 Monoclonal antibody, PBS Only

SMYD4 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2F4B7

Cat no : 66874-1-PBS

Synonyms

KIAA1936, SMYD4, ZMYND21

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Validation Data Gallery

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  WB analysis of MCF-7 using 66874-1-Ig (same clone as 66874-1-PBS)

  MCF-7 cells were subjected to SDS PAGE followed by western blot with 66874-1-Ig (SMYD4 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66874-1-PBS in a different storage buffer formulation.

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Product Information

66874-1-PBS targets SMYD4 in WB, Indirect ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: SMYD4 fusion protein Ag11552
• Full Name: SET and MYND domain containing 4
• Calculated Molecular Weight: 804 aa, 89 kDa
• Observed Molecular Weight: 85-89 kDa
• GenBank Accession Number: BC035077
• Gene Symbol: SMYD4
• Gene ID (NCBI): 114826
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

SMYD4, also named as SET and MYND domain-containing protein 4, is a 804 amino acid protein, which contains 1 MYND-type zinc finger and 1 SET domain. SMYD4 belongs to the class V-like SAM-binding methyltransferase superfamily. SMYD4, as a potential tumor suppressor, plays a critical role in breast carcinogenesis at least partly through inhibiting the expression of Pdgfr-alpha, and could be a novel target for improving treatment of breast cancer. SMYD4 is a muscle-specific transcriptional modulator involved in development.