SLCO1B3/OATP1B3 Polyclonal antibody, PBS Only

• 

  WB analysis using 22815-1-AP (same clone as 22815-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 22815-1-AP (SLCO1B3/OATP1B3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22815-1-PBS in a different storage buffer formulation.

SLCO1B3/OATP1B3 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 22815-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

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Product Information

22815-1-PBS targets SLCO1B3/OATP1B3 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SLCO1B3/OATP1B3 fusion protein Ag18940
• Full Name: solute carrier organic anion transporter family, member 1B3
• Calculated Molecular Weight: 702 aa, 77 kDa
• Observed Molecular Weight: 70-75 kDa
• GenBank Accession Number: BC105597
• Gene Symbol: SLCO1B3
• Gene ID (NCBI): 28234
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9NPD5
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

SLCO1B3, also known as OATP8 or OATP1B3, is a member of Organic Anion Transporting Polypeptides (OATPs) which are sodium-independent organic anion transporters mediating the uptake of a wide range of structurally diverse endogenous and exogenous compounds including bile acids, hormone conjugates, peptides, toxins, as well as a multitude of therapeutic drugs. SLCO1B3 is specifically expressed in liver under normal condition, while its expression has also been observed in cancer tissues like colon, prostate and pancreas. SLCO1B3 is a glycosylated protein and can be detected in the non-glycosylated form at 70-75 kDa(PMID: 21278621).