Product Information
84060-5-PBS targets SLC9A3R2 in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | SLC9A3R2 fusion protein Ag13476 Predict reactive species |
Full Name | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 |
Calculated Molecular Weight | 337 aa, 37 kDa |
Observed Molecular Weight | ~45 kDa |
GenBank Accession Number | BC106001 |
Gene Symbol | SLC9A3R2 |
Gene ID (NCBI) | 9351 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q15599 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
SLC9A3R2, also named as NHERF2, is a member of the Na+/H+ exchanger regulatory factor (NHERF) family of PDZ scaffolding proteins. SLC9A3R2 is needed for cGMP and carbachol-mediated inhibition as well as LPA and dexamethasone-mediated stimulation of NHE3. NHERF1 and NHERF2 are highly homologous structurally to each other but play different roles in the regulation of Na+ and Cl− transport.(PMID: 23612977)