SLC6A18 Polyclonal antibody

SLC6A18 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 17876-1-AP

Synonyms

SLC6A18, Xtrp2

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Validation Data Gallery

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  WB analysis using 17876-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 17876-1-AP (SLC6A18 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HepG2 cells, RAW 264.7 cells, mouse brain tissue, mouse kidney tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

17876-1-AP targets SLC6A18 in WB, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SLC6A18 fusion protein Ag11685
• Full Name: solute carrier family 6, member 18
• Calculated Molecular Weight: 628 aa, 71 kDa
• Observed Molecular Weight: ~70 kDa
• GenBank Accession Number: BC056757
• Gene Symbol: SLC6A18
• Gene ID (NCBI): 348932
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SLC6A18, also known as XTRP2 and B0AT3, belongs to the SLC6 family of proteins. SLC6A18 acts as specific transporters for neurotransmitters, amino acids and osmolytes such as betaine, taurine and creatine. SLC6A18 is highly expressed at the luminal membrane of kidney proximal tubules and displays 50% identity with SLC6A19 (B0AT1), which is the main neutral amino acid transporter in both kidney and small intestine (PMID: 19478081, PMID: 21420947).