SLC39A9 Polyclonal antibody, PBS Only

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  WB analysis using 17607-1-AP (same clone as 17607-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17607-1-AP (SLC39A9 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17607-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 17607-1-AP (same clone as 17607-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 17607-1-AP (SLC39A9 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17607-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 17607-1-AP (same clone as 17607-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 17607-1-AP (SLC39A9 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17607-1-PBS in a different storage buffer formulation.

SLC39A9 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 17607-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Synonyms

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Product Information

17607-1-PBS targets SLC39A9 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SLC39A9 fusion protein Ag11752
• Full Name: solute carrier family 39 (zinc transporter), member 9
• Calculated Molecular Weight: 307 aa, 32 kDa
• Observed Molecular Weight: 25 kDa
• GenBank Accession Number: BC047682
• Gene Symbol: SLC39A9
• Gene ID (NCBI): 55334
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9NUM3
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

Zinc transporter ZIP9 subfamily (SLC39A9) encodes a protein with characteristics of a membrane androgen receptor (mAR). Human ZIP9 is a 307-amino acid protein, which has eight putative transmembrane domains. ZIP9 has also been identified and characterized as a resident protein in the Golgi in DT40 and HeLa cell lines (PMID: 19420709, 23505453). ZIP9 may be present on the cell surface, as well as nuclear and mitochondrial membranes, in human breast and prostate cancer cell lines, where it mediates testosterone induction of apoptosis (PMID: 29952128). Knockout of ZIP9 would lead to zinc accumulation in the secretory pathway, which could influence the general ion homeostasis and in turn the glycosylation outcome (PMID: 36648436).