SLC38A1 Polyclonal antibody, PBS Only

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  WB analysis using 28632-1-AP (same clone as 28632-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 28632-1-AP (SLC38A1 antibody) at dilution of 1:7000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28632-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 28632-1-AP (same clone as 28632-1-PBS)

  WB result of SLC38A1 antibody (28632-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-SLC38A1 transfected Jurkat cells. This data was developed using the same antibody clone with 28632-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 28632-1-AP (same clone as 28632-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28632-1-AP (SLC38A1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28632-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 28632-1-AP (same clone as 28632-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28632-1-AP (SLC38A1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28632-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

SLC38A1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 28632-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Synonyms

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Product Information

28632-1-PBS targets SLC38A1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SLC38A1 fusion protein Ag30088
• Full Name: solute carrier family 38, member 1
• Calculated Molecular Weight: 487 aa, 54 kDa
• Observed Molecular Weight: 54 kDa, 60-70 kDa
• GenBank Accession Number: BC010620
• Gene Symbol: SLC38A1
• Gene ID (NCBI): 81539
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9H2H9
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

SLC38A1 (Sodium-coupled neutral amino acid transporter 1), is also named as SNAT1, which is a symporter that cotransports short-chain neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane (PMID:20599747, PMID:10891391). Inhibition of SLC38A1 reduced tumor growth, cellular migration, invasion, and induced senescence in melanoma cells (PMID:35565278). SLC38A1 was identified as a positive regulator of mTORC1 in neurons, which promoted ischemic brain damage by mTOR-autophagy system (PMID:31552299). SLC38A1 is mainly expressed in brain and placenta.