SLC22A4 Polyclonal antibody, PBS Only

SLC22A4 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 13238-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis using 13238-1-AP (same clone as 13238-1-PBS)

  boiled and 37°C incubated mouse kidney tissue lysates were subjected to SDS PAGE followed by western blot with 13238-1-AP (SLC22A4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13238-1-PBS in a different storage buffer formulation.

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Product Information

13238-1-PBS targets SLC22A4 in WB, Indirect ELISA applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SLC22A4 fusion protein Ag3974
• Full Name: solute carrier family 22 (organic cation/ergothioneine transporter), member 4
• Calculated Molecular Weight: 551 aa, 62 kDa
• Observed Molecular Weight: 62-70 kDa
• GenBank Accession Number: BC028313
• Gene Symbol: SLC22A4
• Gene ID (NCBI): 6583
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

SLC22A4 (solute carrier family 22 member 4), also known as OCTN1. It is expected to be located in cell membrane and mitochondrion membrane. It is strongly expressed in kidney, trachea, bone marrow and fetal liver and in several human cancer cell lines, but not in adult liver (PMID: 9426230). The protein functions as a Na+-dependent and pH-dependent high affinity microbial symporter of potent food-derived antioxidant ergothioeine (PubMed:15795384), which transports one sodium ion with one ergothioeine molecule. The calculated molecular weight of SLC22A4 is 62 kDa, the band of 70 kDa is glycosylated (PMID:26724204).