SLC17A5 Polyclonal antibody, PBS Only

• 

  WB analysis of human kidney using 13320-1-AP (same clone as 13320-1-PBS)

  human kidney tissue were subjected to SDS PAGE followed by western blot with 13320-1-AP (SLC17A5 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13320-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HEK-293 using 13320-1-AP (same clone as 13320-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 13320-1-AP (SLC17A5 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13320-1-PBS in a different storage buffer formulation.

SLC17A5 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 13320-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

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Product Information

13320-1-PBS targets SLC17A5 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SLC17A5 fusion protein Ag3855
• Full Name: solute carrier family 17 (anion/sugar transporter), member 5
• Calculated Molecular Weight: 495 aa, 55 kDa
• Observed Molecular Weight: 31 kDa
• GenBank Accession Number: BC020961
• Gene Symbol: SLC17A5
• Gene ID (NCBI): 26503
• RRID: AB_2187524
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9NRA2
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

SLC17A5 encodes a transmembrane protein, sialin, which transports free sialic acid across the lysosomal membrane. Mutations in sialin result in neurodegenerative sialic acid storage disorders, Salla disease (SD) and infantile sialic acid storage disease (ISSD). In the central nervous system, sialin is more abundant in neurons than in glia. It has been reported to be localized into lysosome in neuron but in plasma membrane in nonneuronal cells (PMID: 15006695).