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SLC17A5 Polyclonal antibody, PBS Only

SLC17A5 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 13320-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of human kidney tissue using SLC17A5 Polyclonal antibody (13320-1-AP)

    WB analysis of human kidney using 13320-1-AP (same clone as 13320-1-PBS)

    human kidney tissue were subjected to SDS PAGE followed by western blot with 13320-1-AP (SLC17A5 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13320-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HEK-293 cells using SLC17A5 Polyclonal antibody (13320-1-AP)

    WB analysis of HEK-293 using 13320-1-AP (same clone as 13320-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 13320-1-AP (SLC17A5 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13320-1-PBS in a different storage buffer formulation.

Product Information

13320-1-PBS targets SLC17A5 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SLC17A5 fusion protein Ag3855
Full Name solute carrier family 17 (anion/sugar transporter), member 5
Calculated Molecular Weight 495 aa, 55 kDa
Observed Molecular Weight 31 kDa
GenBank Accession NumberBC020961
Gene Symbol SLC17A5
Gene ID (NCBI) 26503
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

SLC17A5 encodes a transmembrane protein, sialin, which transports free sialic acid across the lysosomal membrane. Mutations in sialin result in neurodegenerative sialic acid storage disorders, Salla disease (SD) and infantile sialic acid storage disease (ISSD). In the central nervous system, sialin is more abundant in neurons than in glia. It has been reported to be localized into lysosome in neuron but in plasma membrane in nonneuronal cells (PMID: 15006695).