SHC1 Monoclonal antibody

SHC1 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

1A5B1

Cat no : 67194-2-Ig

Synonyms



Tested Applications

Positive WB detected inTT cells, hTERT-RPE1 cells, PANC-1 cells, HeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

67194-2-Ig targets SHC1 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen SHC1 fusion protein Ag25173
Full Name SHC (Src homology 2 domain containing) transforming protein 1
Calculated Molecular Weight 63 kDa
Observed Molecular Weight66 kDa
GenBank Accession NumberNM_183001
Gene Symbol SHC1
Gene ID (NCBI) 6464
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The proto-oncogene SHC family consists of SHCA, SHCB, SHCC, and SHCD4 gene members, which can encode 7 kinds of cohesive molecules. SHC family is widely expressed and functional. The SHC1 gene is located in zone 1, region 2 of human chromosome 1. SHC1 is believed to be involved in inhibiting neuronal apoptosis and regulating the receptor tyrosine kinase pathway. SHC1 sensitizes cancer cells to the 8-Cl-cAMP treatment.

Protocols

Product Specific Protocols
WB protocol for SHC1 antibody 67194-2-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols