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SEC61 Alpha Polyclonal antibody

SEC61alpha Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

ELISA

Conjugate

Unconjugated

Cat no : 15512-1-AP

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of mouse liver tissue using SEC61 Alpha Polyclonal antibody (15512-1-AP)

    WB analysis of mouse liver using 15512-1-AP

    mouse liver tissue were subjected to SDS PAGE followed by western blot with 15512-1-AP (SEC61alpha antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

Product Information

15512-1-AP targets SEC61alpha in ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SEC61alpha fusion protein Ag7693
Full Name Sec61 alpha 1 subunit (S. cerevisiae)
Calculated Molecular Weight 52 kDa
GenBank Accession NumberBC002951
Gene Symbol SEC61alpha
Gene ID (NCBI) 29927
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The SEC61 complex is a major component of the endoplasmic reticulum (ER) translocation site (PMID: 7720858). This complex is composed of three subunits: SEC61alpha, SEC61beta and SEC61gamma. SEC61alpha is a polytopic integral membrane protein. It is a core component of the ER translocation complex, playing a crucial role in the insertion of secretory and membrane polypeptides into the ER (PMID: 9512475).