Product Information
66284-1-PBS targets SDCCAG8 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | SDCCAG8 fusion protein Ag4264 Predict reactive species |
Full Name | serologically defined colon cancer antigen 8 |
Calculated Molecular Weight | 713 aa, 83 kDa |
Observed Molecular Weight | 83 kDa |
GenBank Accession Number | BC032454 |
Gene Symbol | SDCCAG8 |
Gene ID (NCBI) | 10806 |
RRID | AB_2881667 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q86SQ7 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
SDCCAG8, also named as CCCAP and NY-CO-8, plays a role in the establishment of cell polarity and epithelial lumen formation. It may play a role in ciliogenesis. Loss of SDCCAG8 function as a cause of a retinal-renal ciliopathy and validates exome capture analysis for broadly heterogeneous single-gene disorders. SDCCAG8 is localized at both centrioles and interacts directly with OFD1 (oral-facial-digital syndrome 1), which is associated with NPHP-RC.