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SCP3 Monoclonal antibody, PBS Only

SCP3 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1A11F1

Cat no : 66409-1-PBS

Synonyms

COR1, SCP 3, SCP3, SYCP3, synaptonemal complex protein 3

Validation Data Gallery

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  • Western Blot (WB) analysis of human testis tissue using SCP3 Monoclonal antibody (66409-1-Ig)

    WB analysis of human testis using 66409-1-Ig (same clone as 66409-1-PBS)

    human testis tissue were subjected to SDS PAGE followed by western blot with 66409-1-Ig (SYCP3 Antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66409-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of DU 145 cells using SCP3 Monoclonal antibody (66409-1-Ig)

    WB analysis of DU 145 using 66409-1-Ig (same clone as 66409-1-PBS)

    DU 145 cells were subjected to SDS PAGE followed by western blot with 66409-1-Ig (SYCP3 Antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66409-1-PBS in a different storage buffer formulation.

Product Information

66409-1-PBS targets SCP3 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen SCP3 fusion protein Ag19330
Full Name synaptonemal complex protein 3
Calculated Molecular Weight 236 aa, 28 kDa
Observed Molecular Weight 30 kDa
GenBank Accession NumberBC062662
Gene Symbol SYCP3
Gene ID (NCBI) 50511
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

SYCP3 is an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. SYCP3 is required for centromere pairing during meiosis in male germ cells. SYCP3 is also required for normal meiosis during spermatogenesis and male fertility. Mutations in SYCP3 are associated with azoospermia in males and susceptibility to pregnancy loss in females.