SCP3 Monoclonal antibody, PBS Only

• 

  WB analysis of human testis using 66409-1-Ig (same clone as 66409-1-PBS)

  human testis tissue were subjected to SDS PAGE followed by western blot with 66409-1-Ig (SYCP3 Antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66409-1-PBS in a different storage buffer formulation.

• 

  WB analysis of DU 145 using 66409-1-Ig (same clone as 66409-1-PBS)

  DU 145 cells were subjected to SDS PAGE followed by western blot with 66409-1-Ig (SYCP3 Antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66409-1-PBS in a different storage buffer formulation.

SCP3 Monoclonal Antibody for WB, Indirect ELISA

Cat No. 66409-1-PBS

Clone No.1A11F1

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

COR1, SCP 3, SCP3, SYCP3, synaptonemal complex protein 3

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Product Information

66409-1-PBS targets SCP3 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: SCP3 fusion protein Ag19330
• Full Name: synaptonemal complex protein 3
• Calculated Molecular Weight: 236 aa, 28 kDa
• Observed Molecular Weight: 30 kDa
• GenBank Accession Number: BC062662
• Gene Symbol: SYCP3
• Gene ID (NCBI): 50511
• RRID: AB_2881781
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q8IZU3
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

SYCP3 is an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. SYCP3 is required for centromere pairing during meiosis in male germ cells. SYCP3 is also required for normal meiosis during spermatogenesis and male fertility. Mutations in SYCP3 are associated with azoospermia in males and susceptibility to pregnancy loss in females.