S100A7/Psoriasin Polyclonal antibody, PBS Only

S100A7/Psoriasin Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 13061-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis of MCF-7 using 13061-1-AP (same clone as 13061-1-PBS)

  MCF-7 cells were subjected to SDS PAGE followed by western blot with 13061-1-AP (S100A7/Psoriasin antibody at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13061-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human oesophagus cancer using 13061-1-AP (same clone as 13061-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human oesophagus cancer tissue slide using 13061-1-AP (S100A7/Psoriasin antibody at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13061-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human oesophagus cancer using 13061-1-AP (same clone as 13061-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human oesophagus cancer tissue slide using 13061-1-AP (S100A7/Psoriasin antibody at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 13061-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 13061-1-AP (same clone as 13061-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 13061-1-AP (S100A7/Psoriasin antibody at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13061-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 13061-1-AP (same clone as 13061-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 13061-1-AP (S100A7/Psoriasin antibody at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 13061-1-PBS in a different storage buffer formulation.

• 

  IF Staining of MCF-7 using 13061-1-AP (same clone as 13061-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed MCF-7 cells using S100A7/Psoriasin antibody (13061-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13061-1-PBS in a different storage buffer formulation.

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Product Information

13061-1-PBS targets S100A7/Psoriasin in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: S100A7/Psoriasin fusion protein Ag3738
• Full Name: S100 calcium binding protein A7
• Calculated Molecular Weight: 101 aa, 11 kDa
• Observed Molecular Weight: 11 kDa
• GenBank Accession Number: BC034687
• Gene Symbol: S100A7/Psoriasin
• Gene ID (NCBI): 6278
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

S100A7 (psoriasin), a member of the S100 protein family, is a well-known antimicrobial peptide and a signaling molecule which regulates cellular function and is expressed in many squamous cell carcinomas (SCCs), such as SCC of the skin. It is an EF-hand type calcium binding protein localized in epithelial cells, regulates cell proliferation and differentiation. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.