RTN2 Polyclonal antibody, PBS Only

• Featured Product
• KD/KO Validated

RTN2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11168-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis of mouse skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11168-1-AP (RTN2 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

  human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11168-1-AP (RTN2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11168-1-AP (RTN2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11168-1-AP (RTN2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

  human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11168-1-AP (RTN2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle slide using 11168-1-AP (RTN2 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle slide using 11168-1-AP (RTN2 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

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Product Information

11168-1-PBS targets RTN2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: RTN2 fusion protein Ag1655
• Full Name: reticulon 2
• Calculated Molecular Weight: 59 kDa, 51 kDa, 22 kDa
• Observed Molecular Weight: 20-23 kDa
• GenBank Accession Number: BC014244
• Gene Symbol: RTN2
• Gene ID (NCBI): 6253
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Reticulon (RTN) proteins are a group of membrane-bound proteins that largely reside in endoplasmic reticulum (ER) (PMID: 18177508). Reticulon proteins share a common sequence feature, the reticulon homology domain (RHD). They are involved in shaping the tubular endoplasmic reticulum network, membrane trafficking, inhibition of axonal growth, and apoptosis (PMID: 24218324). Four mammalian reticulons (RTN1-4) exist. Human RTN2 gene produces three isoforms termed RTN2-A, RTN2-B, and RTN2-C. Isoform RTN2-C has a calculated molecular weight of 22 kDa and is highly expressed in skeletal muscle.