RIAM Monoclonal antibody, PBS Only
RIAM Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
Human, Mouse
Applications
WB, IHC, IF-P, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2F8A2
Cat no : 67143-1-PBS
Synonyms
Validation Data Gallery
Product Information
67143-1-PBS targets RIAM in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with Human, Mouse samples.
Tested Reactivity | Human, Mouse |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | RIAM fusion protein Ag4602 |
Full Name | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
Calculated Molecular Weight | 666 aa, 73 kDa |
Observed Molecular Weight | 100 kDa |
GenBank Accession Number | BC035636 |
Gene Symbol | RIAM |
Gene ID (NCBI) | 54518 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
APBB1IP gene encodes a Rap1-GTP-interacting adapter molecule (RIAM) which is an important protein in Rap1-mediated integrin activation and adhesion. Rap1 is a small GTPase frequently activated in tumors such as melanoma and prostate cancer. RIAM is widely expressed with high expression in thymus, spleen, lymph node, bone marrow and peripheral leukocytes. RIAM may function in the signal transduction from Ras activation to actin cytoskeletal remodeling. The observed molecular weight of RIAM is about 100 kDa.