RHOQ/TC10 Polyclonal antibody

• Featured Product
• KD/KO Validated

RHOQ/TC10 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Publications

3

Cat no : 17805-1-AP

Synonyms

ARHQ, Ras like protein TC10, RASL7A, RHOQ, TC10, TC10A

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Validation Data Gallery

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  WB analysis using 17805-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 17805-1-AP (RHOQ/TC10 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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  WB analysis of human brain using 17805-1-AP

  human brain tissue were subjected to SDS PAGE followed by western blot with 17805-1-AP (TC10 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: mouse brain tissue, human brain tissue, rat brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• KD/KO: See 2 publications below
• WB: See 2 publications below

Product Information

The immunogen of 17805-1-AP is RHOQ/TC10 Fusion Protein expressed in E. coli.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: RHOQ/TC10 fusion protein Ag12078
• Full Name: ras homolog gene family, member Q
• Calculated Molecular Weight: 205 aa, 23 kDa
• Observed Molecular Weight: 23 kDa
• GenBank Accession Number: BC070485
• Gene Symbol: RHOQ/TC10
• Gene ID (NCBI): 23433
• RRID: AB_10732837
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Publications

Species	Application	Title
mouse	WB	J Immunol; The Small Rho GTPase TC10 Modulates B Cell Immune Responses.; Authors - Marianne Burbage ; KO Validated
mouse	WB	J Neurochem; TC10, a Rho family GTPase, is required for efficient axon regeneration in a neuron-autonomous manner.; Authors - Shingo Koinuma ; KO Validated
rat		Genes Cells; cAMP-induced activation of protein kinase A and p190B RhoGAP mediates down-regulation of TC10 activity at the plasma membrane and neurite outgrowth.; Authors - Shingo Koinuma