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RB1CC1 Monoclonal antibody, PBS Only

RB1CC1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1G8C8

Cat no : 68564-1-PBS

Synonyms

CC1, DRAGOU14, FIP200, KIAA0203, RB1 inducible coiled coil 1, RB1CC1, RBICC

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using RB1CC1 Monoclonal antibody (68564-1-Ig)

    WB analysis using 68564-1-Ig (same clone as 68564-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68564-1-Ig (RB1CC1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68564-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using RB1CC1 Monoclonal antibody (68564-1-Ig)

    WB analysis using 68564-1-Ig (same clone as 68564-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68564-1-Ig (RB1CC1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68564-1-PBS in a different storage buffer formulation.

Product Information

68564-1-PBS targets RB1CC1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

Tested Reactivity Human, mouse, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen RB1CC1 fusion protein Ag10508
Full Name RB1-inducible coiled-coil 1
Calculated Molecular Weight 1594 aa, 183 kDa
Observed Molecular Weight200 kDa
GenBank Accession NumberBC017556
Gene Symbol RB1CC1
Gene ID (NCBI) 9821
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

RB1CC1, also named as RBICC or FIP200, is implicated in the regulation of RB1 expression and functions as a DNA-binding transcription factor. It is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Its expression is, thus, a prerequisite for myogenic differentiation. Involved in autophagy. RB1CC1 is required for autophagosome formation. It is probably involved in the tumorigenesis of breast cancer. RB1CC1 is frequently mutated in breast cancer and shows characteristics of a classical tumor suppressor gene.