RAD17 Monoclonal antibody, PBS Only

RAD17 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1F12D8

Cat no : 68539-1-PBS

Synonyms

CCYC, FLJ41520, HRAD17, R24L, RAD17, RAD17 homolog (S. pombe), RAD17SP, RAD24, RF C/activator 1 homolog

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Validation Data Gallery

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  WB analysis using 68539-1-Ig (same clone as 68539-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68539-1-Ig (RAD17 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68539-1-PBS in a different storage buffer formulation.

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Product Information

68539-1-PBS targets RAD17 in WB, Indirect ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: RAD17 fusion protein Ag4348
• Full Name: RAD17 homolog (S. pombe)
• Calculated Molecular Weight: 681 aa, 71 kDa
• Observed Molecular Weight: 70-80 kDa
• GenBank Accession Number: BC032304
• Gene Symbol: RAD17
• Gene ID (NCBI): 5884
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Rad17, a component of the checkpoint clamp loader complex (RAD17/RFC), was originally initially identified as a DNA damage checkpoint protein. Rad17 participates in cell cycle control and DNA damage repair. Rad17 phosphorylation by ATR (ataxia telangiectasia mutated and Rad3-related) kinase is indispensable for the recruitment of Claspin and the activation of Chk1 in response to genotoxic stress.