RAB20 Polyclonal antibody

• Featured Product
• KD/KO Validated

RAB20 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Publications

4

Cat no : 11616-1-AP

Synonyms

RAB20, Ras related protein Rab 20

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Validation Data Gallery

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Published Applications

• KD/KO: See 3 publications below
• WB: See 4 publications below
• IF: See 4 publications below

Product Information

11616-1-AP targets RAB20 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: RAB20 fusion protein Ag2193
• Full Name: RAB20, member RAS oncogene family
• Calculated Molecular Weight: 26 kDa
• Observed Molecular Weight: 26-29 kDa
• GenBank Accession Number: BC026025
• Gene Symbol: RAB20
• Gene ID (NCBI): 55647
• RRID: AB_2877784
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

RAB20 is a member of RAS oncogene family, it has no close relationship to any other members of RAB subfamily which consists of small GTP-binding proteins involved in the regulation of intracellullar vesicular transport. Firstly found highly expressed on the apical side of kidney tubuel epithelial cells, RAB20 was speculated to be involved in apical endocytosi and recylcing processes. So far, its function is not well known, however, RAB20 is recently found higher expressed in pancreatic adenocarcinomas than normal pancreas, which is proved by WB and IHC analyses, suggesting its promising role in diagnosis of pancreatic carcinogenesis. Catalog#11616-1-AP is a rabbit polyclonal antibody raised against full-length of human RAB20.

Publications

Species	Application	Title
mouse	WB,IF	Cell Host Microbe; A Rab20-Dependent Membrane Trafficking Pathway Controls M. tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity.; Authors - Laura Schnettger ; KO Validated
mouse	WB,IF	J Cell Sci; Identification of an immune-regulated phagosomal Rab cascade in macrophages.; Authors - Gang Pei ; KD Validated
mouse	WB,IF	Mol Biol Cell; Interferon-gamma-inducible Rab20 regulates endosomal morphology and EGFR degradation in macrophages.; Authors - Gang Pei ; KD Validated
mouse	IF,WB	Front Mol Neurosci; Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction; Authors - Jia Guo