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  • KD/KO Validated

RAB20 Polyclonal antibody

RAB20 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Cat no : 11616-1-AP

Synonyms

RAB20, Ras related protein Rab 20



Product Information

11616-1-AP targets RAB20 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivitymouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen RAB20 fusion protein Ag2193
Full Name RAB20, member RAS oncogene family
Calculated Molecular Weight 26 kDa
Observed Molecular Weight 26-29 kDa
GenBank Accession NumberBC026025
Gene Symbol RAB20
Gene ID (NCBI) 55647
RRIDAB_2877784
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

RAB20 is a member of RAS oncogene family, it has no close relationship to any other members of RAB subfamily which consists of small GTP-binding proteins involved in the regulation of intracellullar vesicular transport. Firstly found highly expressed on the apical side of kidney tubuel epithelial cells, RAB20 was speculated to be involved in apical endocytosi and recylcing processes. So far, its function is not well known, however, RAB20 is recently found higher expressed in pancreatic adenocarcinomas than normal pancreas, which is proved by WB and IHC analyses, suggesting its promising role in diagnosis of pancreatic carcinogenesis. Catalog#11616-1-AP is a rabbit polyclonal antibody raised against full-length of human RAB20.

Publications

SpeciesApplicationTitle
mouseWB,IF

Cell Host Microbe

A Rab20-Dependent Membrane Trafficking Pathway Controls M. tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity.

Authors - Laura Schnettger
  • KO Validated
mouseWB,IF

J Cell Sci

Identification of an immune-regulated phagosomal Rab cascade in macrophages.

Authors - Gang Pei
  • KD Validated
mouseWB,IF

Mol Biol Cell

Interferon-gamma-inducible Rab20 regulates endosomal morphology and EGFR degradation in macrophages.

Authors - Gang Pei
  • KD Validated
mouseIF,WB

Front Mol Neurosci

Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction

Authors - Jia Guo