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  • Featured Product
  • KD/KO Validated

QKI Polyclonal antibody, PBS Only

QKI Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 13169-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using QKI Polyclonal antibody (13169-1-AP)

    WB analysis using 13169-1-AP (same clone as 13169-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13169-1-AP (QKI antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13169-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of K-562 cells using QKI Polyclonal antibody (13169-1-AP)

    IP experiment of K-562 using 13169-1-AP (same clone as 13169-1-PBS)

    IP result of anti-QKI (IP:13169-1-AP, 4ug; Detection:13169-1-AP 1:400) with K-562 cells lysate 3600ug. This data was developed using the same antibody clone with 13169-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human stomach cancer tissue using QKI Polyclonal antibody (13169-1-AP)

    IHC staining of human stomach cancer using 13169-1-AP (same clone as 13169-1-PBS)

    Immunohistochemical analysis of paraffin-embedded stomach cancer slide using 13169-1-AP (QKI antibody) at dilution of 1:300 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13169-1-PBS in a different storage buffer formulation.

Product Information

13169-1-PBS targets QKI in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen QKI fusion protein Ag3822
Full Name quaking homolog, KH domain RNA binding (mouse)
Calculated Molecular Weight 341 aa, 38 kDa
Observed Molecular Weight 38 kDa
GenBank Accession NumberBC019917
Gene Symbol QKI
Gene ID (NCBI) 9444
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

QKI (Quaking) is RNA-binding protein that plays a central role in myelinization (PMID: 16641098). It regulates pre-mRNA splicing, mRNA export and protein translation (PMID: 16641098). It acts upstream of or within several processes, including long-chain fatty acid biosynthetic process, positive regulation of macromolecule metabolic process and vasculogenesis. QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism. It is expressed in the frontal cortex of brain (PMID: 16342280).