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Prothymosin Alpha Polyclonal antibody, PBS Only

Prothymosin Alpha Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 10480-1-PBS

Synonyms

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human lymphoma tissue using Prothymosin Alpha Polyclonal antibody (10480-1-AP)

    IHC staining of human lymphoma using 10480-1-AP (same clone as 10480-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma using 10480-1-AP (Prothymosin alpha antibody) at dilution of 1:100 (under 25x lens). This data was developed using the same antibody clone with 10480-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lymphoma tissue using Prothymosin Alpha Polyclonal antibody (10480-1-AP)

    IHC staining of human lymphoma using 10480-1-AP (same clone as 10480-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 10480-1-AP (Prothymosin alpha antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10480-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lymphoma tissue using Prothymosin Alpha Polyclonal antibody (10480-1-AP)

    IHC staining of human lymphoma using 10480-1-AP (same clone as 10480-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 10480-1-AP (Prothymosin alpha antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10480-1-PBS in a different storage buffer formulation.

Product Information

10480-1-PBS targets Prothymosin Alpha in IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Prothymosin Alpha fusion protein Ag0732
Full Name prothymosin, alpha
Calculated Molecular Weight 12 kDa
GenBank Accession NumberBC003510
Gene Symbol Prothymosin Alpha/PTMA
Gene ID (NCBI) 5757
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Prothymosin alpha (PTMA) is a nuclear protein possessing a number of cellular functions including cell survival. PTMA is identified to be localized in the nuclei of neurons, while it is found in both nuclei and cytoplasm in the astrocytes and microglia of adult brai. PTMA inhibits the neuronal necrosis induced by serum-free starvation or ischemia-reperfusion stress, which causes a rapid internalization of GLUT1/4, leading a decrease in glucose uptake and cellular ATP levels. Extensive research on PTMA showed that it is of clinical significance and potential medical use as they may serve as a molecular marker for cancer prognosis and/or as therapeutic agents for treating immunodeficiencies, autoimmune diseases and malignancies.