Plasminogen Polyclonal antibody, PBS Only
Plasminogen Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, IF/ICC, Indirect ELISA
Conjugate
Unconjugated
Cat no : 17462-1-PBS
Synonyms
Validation Data Gallery
Product Information
17462-1-PBS targets Plasminogen in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Plasminogen fusion protein Ag11217 |
Full Name | plasminogen |
Calculated Molecular Weight | 810 aa, 91 kDa |
Observed Molecular Weight | 97 kDa |
GenBank Accession Number | BC060513 |
Gene Symbol | Plasminogen |
Gene ID (NCBI) | 5340 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Plasminogen is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasminogen plays an important role in fibrinolysis as well as wound healing, cell migration, tissue modeling and angiogenesis. Plasminogen is synthesized in the liver, and it circulates in the blood, with a half-life of 2.2 days. Plasminogen is the precursor of plasmin, which lyses fibrin clots to fibrin degradation products (FDP) and D-dimer; the conversion to active protease is mediated by tissue-type (tPA) and urokinase-type (uPA) plasminogen activators. Defects in plasminogen are likely a cause of thrombophilia and ligneous conjunctivitis.