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PSMD2 Monoclonal antibody, PBS Only

PSMD2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1G7G5

Cat no : 67770-1-PBS

Synonyms

TRAP2, S2, Rpn1, P97, 26S proteasome non-ATPase regulatory subunit 2

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using PSMD2 Monoclonal antibody (67770-1-Ig)

    WB analysis using 67770-1-Ig (same clone as 67770-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67770-1-Ig (PSMD2 antibody) at dilution of 1:50000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67770-1-PBS in a different storage buffer formulation.

Product Information

67770-1-PBS targets PSMD2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen PSMD2 fusion protein Ag6543
Full Name proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
Calculated Molecular Weight 100 kDa
Observed Molecular Weight100 kDa
GenBank Accession NumberBC002368
Gene Symbol PSMD2
Gene ID (NCBI) 5708
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Tumor necrosis factor type 1 receptor-associated protein 2 (TRAP2), encoded by PSMD2 gene, is a non-ATPase regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. TRAP2 may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor.