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PRODH Monoclonal antibody, PBS Only

PRODH Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat, rabbit, pig

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2C3G5

Cat no : 68621-1-PBS

Synonyms

FLJ33744, HSPOX2, p53 induced gene 6 protein, PIG6, POX, POX2, PRODH, PRODH1, PRODH2, Proline oxidase, Proline oxidase 2, SCZD4, TP53I6

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using PRODH Monoclonal antibody (68621-1-Ig)

    WB analysis using 68621-1-Ig (same clone as 68621-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68621-1-Ig (PRODH antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68621-1-PBS in a different storage buffer formulation.

Product Information

68621-1-PBS targets PRODH in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, rabbit, pig samples.

Tested Reactivity Human, mouse, rat, rabbit, pig
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen PRODH fusion protein Ag18429
Full Name proline dehydrogenase (oxidase) 1
Calculated Molecular Weight 600 aa, 68 kDa
Observed Molecular Weight56 kDa, 66 kDa
GenBank Accession NumberBC118597
Gene Symbol PRODH
Gene ID (NCBI) 5625
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

PRODH(Proline dehydrogenase 1, mitochondrial) is also named as PIG6, HSPOX2, PRODH1, PRODH2, POX, SCZD4, TP53I6 and belongs to the proline oxidase family. It is an oxidoreductase involved in the transfer of redox potential across the mitochondrial membrane and catalyzes the rate-limiting oxidation of proline to pyrroline- 5-carboxylate (P5C). High PRODH activity is sufficient to induce mitochondria-mediated apoptosis in the presence of proline. Defects in PRODH are the cause of hyperprolinemia type 1 (HP-1) and defects in PRODH are associated with susceptibility to schizophrenia type 4 (SCZD4). This protein has 3 isoforms produced by alternative splicing with the molecular mass of 68 kDa, 59 kDa and 56 kDa.