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PROC Polyclonal antibody, PBS Only

PROC Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 25382-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of mouse liver tissue using PROC Polyclonal antibody (25382-1-AP)

    WB analysis of mouse liver using 25382-1-AP (same clone as 25382-1-PBS)

    mouse liver tissue were subjected to SDS PAGE followed by western blot with 25382-1-AP (PROC Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25382-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human liver tissue using PROC Polyclonal antibody (25382-1-AP)

    IHC staining of human liver using 25382-1-AP (same clone as 25382-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 25382-1-AP (PROC Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 25382-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human liver tissue using PROC Polyclonal antibody (25382-1-AP)

    IHC staining of human liver using 25382-1-AP (same clone as 25382-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 25382-1-AP (PROC Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 25382-1-PBS in a different storage buffer formulation.

Product Information

25382-1-PBS targets PROC in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PROC fusion protein Ag11328
Full Name protein C (inactivator of coagulation factors Va and VIIIa)
Calculated Molecular Weight 461 aa, 52 kDa
Observed Molecular Weight 52 kDa
GenBank Accession NumberBC034377
Gene Symbol PROC
Gene ID (NCBI) 5624
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

PROC belongs to the peptidase S1 family. PROC is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids (PMID:25618265). It exerts a protective effect on the endothelial cell barrier function (PMID:25651845).