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Product Information

25382-1-PBS targets PROC in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PROC fusion protein Ag11328 Predict reactive species
Full Name protein C (inactivator of coagulation factors Va and VIIIa)
Calculated Molecular Weight 461 aa, 52 kDa
Observed Molecular Weight 52 kDa
GenBank Accession NumberBC034377
Gene Symbol PROC
Gene ID (NCBI) 5624
RRIDAB_2880052
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP04070
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

PROC belongs to the peptidase S1 family. PROC is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids (PMID:25618265). It exerts a protective effect on the endothelial cell barrier function (PMID:25651845).

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