Product Information
81833-1-PBS targets PRDX3 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | PRDX3 fusion protein Ag1062 Predict reactive species |
Full Name | peroxiredoxin 3 |
Calculated Molecular Weight | 27 kDa |
Observed Molecular Weight | 28 kDa |
GenBank Accession Number | BC007062 |
Gene Symbol | PRDX3 |
Gene ID (NCBI) | 10935 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P30048 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
PRDX3(Peroxiredoxin 3), also named as AOP1, HBC189 and MER5, belongs to the ahpC/TSA family. It is involved in redox regulation of the cell and protects radical-sensitive enzymes from oxidative damage by a radical-generating system. PRDX3 is required for MYC-mediated proliferation, transformation, and apoptosis after glucose withdrawal and essential for maintaining mitochondrial mass and membrane potential in transformed rat and human cells (PMID:12011429). PRDX3 acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.