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PRDM2 Polyclonal antibody, PBS Only

PRDM2 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 27718-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of HeLa cells using PRDM2 Polyclonal antibody (27718-1-AP)

    WB analysis of HeLa using 27718-1-AP (same clone as 27718-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 27718-1-AP (PRDM2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27718-1-PBS in a different storage buffer formulation.

Product Information

27718-1-PBS targets PRDM2 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PRDM2 fusion protein Ag26769
Full Name PR domain containing 2, with ZNF domain
Calculated Molecular Weight 189 kDa
Observed Molecular Weight 250-280 kDa
GenBank Accession NumberNM_001007257
Gene Symbol PRDM2
Gene ID (NCBI) 7799
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

PRDM2, also named as KMT8, RIZ, is a 1718 amino acid protein, which belongs to the class V-like SAM-binding methyltransferase superfamily. PRDM2 localizes in the nucleus and is highly expressed in retinoblastoma cell lines and in brain tumors and is also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isoform 3. PRDM2 as a S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. The calculated molecular weight of PRDM2 is about 189 kDa. PRDM2 exists some isoforms with 250 kDa and 280 kDa. (PMID: 26040698)