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PRDM10 Polyclonal antibody, PBS Only

PRDM10 Polyclonal Antibody for WB, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 23827-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of HEK-293 cells using PRDM10 Polyclonal antibody (23827-1-AP)

    WB analysis of HEK-293 using 23827-1-AP (same clone as 23827-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 23827-1-AP (PRDM10 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23827-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of mouse testis tissue using PRDM10 Polyclonal antibody (23827-1-AP)

    IP experiment of mouse testis using 23827-1-AP (same clone as 23827-1-PBS)

    IP result of anti-PRDM10 (IP:23827-1-AP, 5ug; Detection:23827-1-AP 1:500) with mouse testis tissue lysate 8000ug. This data was developed using the same antibody clone with 23827-1-PBS in a different storage buffer formulation.

Product Information

23827-1-PBS targets PRDM10 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PRDM10 fusion protein Ag20605
Full Name PR domain containing 10
Calculated Molecular Weight 1156 aa, 131 kDa
Observed Molecular Weight 120-150 kDa
GenBank Accession NumberBC112934
Gene Symbol PRDM10
Gene ID (NCBI) 56980
RRIDAB_2879330
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

PRDM10 is a member of PRDM family, which contains a PR(PRDI-BF1 and RIZ homology) domain, and PRDM is also a subgroup of PR/SET transcription factor family for its PR domain is similar to the catalytic motif of the SET domain of histone methyltransferase(HMTase). Thus PRDM is suggested involve in the regulation of genome expression and chromatin remodeling. PRDM10 shares characteristics with the PR/SET faimly and clusters of zinc fingers DNA binding motifs. It's postualated PRDM10 has an essential role in regulating gene expression and tissue differentiation and a gene repressor. It may play a role in the pathogenesis of gangliosidosis.