PPP2R5A Polyclonal antibody, PBS Only

PPP2R5A Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 29365-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis using 29365-1-AP (same clone as 29365-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29365-1-AP (PPP2R5A antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29365-1-PBS in a different storage buffer formulation.

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Product Information

29365-1-PBS targets PPP2R5A in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: PPP2R5A fusion protein Ag31072
• Full Name: protein phosphatase 2, regulatory subunit B', alpha isoform
• Calculated Molecular Weight: 486 aa, 56 kDa
• Observed Molecular Weight: 50-56 kDa
• GenBank Accession Number: BC022474
• Gene Symbol: PPP2R5A
• Gene ID (NCBI): 5525
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Protein phosphatase 2, regulatory subunit B (B56), alpha isoform (PPP2R5A) is one of the regulatory subunits of the protein phosphatase 2A (PP2A), which is a major member of protein serine/threonine phosphatases in cells. PPP2R5A can regulate the cellular location, substrate specification and protein phosphatase function of PP2A, through which PPP2R5A plays an important role in many cellular activities. It has been reported that PPP2R5A relates with many diseases including cancers by regulating many crucial signaling pathways involved in P53, Bcl-2, CDK, MAPK, JAK/STAT, c-Myc and β-Catenin.