PPBP,NAP2 Polyclonal antibody, PBS Only

PPBP,NAP2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 13313-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis of mouse liver using 13313-1-AP (same clone as 13313-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 13313-1-AP (PPBP,NAP2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13313-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human plasma using 13313-1-AP (same clone as 13313-1-PBS)

  human blood were subjected to SDS PAGE followed by western blot with 13313-1-AP (PPBP,NAP2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13313-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human liver using 13313-1-AP (same clone as 13313-1-PBS)

  human liver tissue were subjected to SDS PAGE followed by western blot with 13313-1-AP (PPBP,NAP2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13313-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 13313-1-AP (same clone as 13313-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 13313-1-AP (PPBP,NAP2 antibody at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13313-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 13313-1-AP (same clone as 13313-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 13313-1-AP (PPBP,NAP2 antibody at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 13313-1-PBS in a different storage buffer formulation.

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Product Information

13313-1-PBS targets PPBP,NAP2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: PPBP,NAP2 fusion protein Ag4147
• Full Name: pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
• Calculated Molecular Weight: 128 aa, 14 kDa
• Observed Molecular Weight: 8-14 kDa
• GenBank Accession Number: BC028217
• Gene Symbol: PPBP
• Gene ID (NCBI): 5473
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

PPBP, slso named as NAP2, or β-Thromboglobulin, is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.