PI3 Kinase p55 Gamma Polyclonal antibody

PI3 Kinase p55 Gamma Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Publications

6

Cat no : 55036-1-AP

Synonyms

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Validation Data Gallery

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Published Applications

• WB: See 6 publications below

Product Information

55036-1-AP targets PI3 Kinase p55 Gamma in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
• Calculated Molecular Weight: 54 kDa
• GenBank Accession Number: NM_003629
• Gene Symbol: PI3 Kinase p55 Gamma
• Gene ID (NCBI): 8503
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

PIK3R3, also named as p55PIK, belongs to the PI3K p85 subunit family. It binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During INS stimulation, it also binds to IRS-1. It is a component of a heterodimer of p110 (catalytic) and p55 (regulatory) subunits. The antibody is specific to PIK3R3.

Publications

Species	Application	Title
mouse	WB	RNA Biol; MicroRNA-432 targeting E2F3 and P55PIK inhibits myogenesis through PI3K/AKT/mTOR signaling pathway.; Authors - Meilin Ma
human	WB	Mol Biol Cell; MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway.; Authors - Xu Lin L
human	WB	Tumour Biol; MiR-511 inhibits growth and metastasis of human hepatocellular carcinoma cells by targeting PIK3R3.; Authors - Gang Cao
rat	WB	Transl Androl Urol; Study on the mechanism of aging-related erectile dysfunction based on bioinformatics and experimental verification; Authors - Taotao Sun
human	WB	Tumour Biol; Upregulation of HOXB7 promotes the tumorigenesis and progression of gastric cancer and correlates with clinical characteristics.; Authors - Jia-Qin Cai
rat	WB	Andrology; Saxagliptin alleviates erectile dysfunction through increasing SDF-1 in diabetes mellitus; Authors - Taotao Sun