Product Information
20933-1-PBS targets PHIP in WB, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | PHIP fusion protein Ag14968 Predict reactive species |
Full Name | pleckstrin homology domain interacting protein |
Calculated Molecular Weight | 1821 aa, 207 kDa |
Observed Molecular Weight | 207 kDa |
GenBank Accession Number | BC008909 |
Gene Symbol | PHIP |
Gene ID (NCBI) | 55023 |
RRID | AB_10733522 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q8WWQ0 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
PHIP is a protein that binds to the insulin receptor substrate 1 protein and regulates glucose transporter translocation in skeletal muscle cells. PHIP may also regulate growth and survival of pancreatic beta cells. Elevated copy number of this gene may be associated with melanoma severity and the encoded protein may promote melanoma metastasis in human patients.