Product Information
15481-1-PBS targets PEX11A in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | PEX11A fusion protein Ag7797 Predict reactive species |
Full Name | peroxisomal biogenesis factor 11 alpha |
Calculated Molecular Weight | 28 kDa |
Observed Molecular Weight | 28 kDa |
GenBank Accession Number | BC009697 |
Gene Symbol | PEX11A |
Gene ID (NCBI) | 8800 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | O75192 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
Peroxisomes are ubiquitous organelles bound by a single membrane. Peroxisomal biogenesis factor 11 alpha (PEX11A) is one of PEX11 gene family members involved in peroxisome elongation. PEX11A is highly expressed in the kidney and liver (PMID: 25113963). PEX11A deficiency will impaire peroxisome elongation, leading to the reduction of functional peroxisome, eventually leading to the reduction of fatty acid oxidation capacity and the formation of steatosis (PMID: 23169785; PMID: 25113963)