Mouse monoclonal antibodies of IgM isotype can be detected with "anti-mouse IgG (H+L)" secondary antibodies.
Product Information
67651-1-PBS targets PDLIM5 in WB, Indirect ELISA applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | PDLIM5 fusion protein Ag25059 Predict reactive species |
| Full Name | PDZ and LIM domain 5 |
| Calculated Molecular Weight | 64 kDa |
| Observed Molecular Weight | 63-69 kDa |
| GenBank Accession Number | BC008741 |
| Gene Symbol | PDLIM5 |
| Gene ID (NCBI) | 10611 |
| RRID | AB_2882850 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Euglobulin precipitation |
| UNIPROT ID | Q96HC4 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
PDLIM5 (PDZ and LIM domain 5), formerly known as enigma homolog (ENH), is a cytoplasmic protein containing PDZ domain and LIM domain at N terminus and C terminus, respectively. PDLIM5 gene generates several splicing variants, EZH1 to EZH4. The long isoform, ENH1, is widely expressed in various tissues including heart, brain, spleen, liver and kidney. In comparison, shorter isoforms that lack the LIM motifs are expressed in cardiac (ENH3) and skeletal muscle (ENH2, ENH3, and ENH4). ENH1 is essential for differentiation of striated muscles through interaction with other proteins. In addition, PDLIM5 is also involved in mood disorders, such as schizophrenia, bipolar disorder, and major depression.
