PDIR Polyclonal antibody, PBS Only

• Featured Product
• KD/KO Validated

PDIR Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 29593-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis using 29593-1-AP (same clone as 29593-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29593-1-AP (PDIR antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29593-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 29593-1-AP (same clone as 29593-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29593-1-AP (PDIR antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29593-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 29593-1-AP (same clone as 29593-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 29593-1-AP (PDIR antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29593-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 29593-1-AP (same clone as 29593-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 29593-1-AP (PDIR antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29593-1-PBS in a different storage buffer formulation.

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Product Information

29593-1-PBS targets PDIR in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: PDIR fusion protein Ag31479
• Full Name: protein disulfide isomerase family A, member 5
• Calculated Molecular Weight: 60 kDa
• Observed Molecular Weight: 60 kDa
• GenBank Accession Number: BC001625
• Gene Symbol: PDIR
• Gene ID (NCBI): 10954
• RRID: AB_2918329
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

PDIR(Protein disulfide isomerase-related protein), also known as PDIA5 (Protein Disulfide Isomerase Family A Member 5), is a member of the PDI gene family and also exhibits chaperone-like activity. PDIR protein is correlated with immune infiltration, which is highly expressed in glioma and participates in glioma progression(PMID: 33664747). PDIR contributes to disulfide bond rearrangement in ATF6α under stress conditions that necessary for ATF6α activation upon ER stress(PMID: 24636989).