- Featured Product
- KD/KO Validated
PDH E1 Alpha Monoclonal antibody, PBS Only
PDH E1 Alpha Monoclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
human
Applications
WB, IHC, IF/ICC, IP, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2B3C10
Cat no : 66119-1-PBS
Synonyms
Validation Data Gallery
Product Information
66119-1-PBS targets PDH E1 Alpha in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | PDH E1 Alpha fusion protein Ag12556 |
Full Name | pyruvate dehydrogenase (lipoamide) alpha 1 |
Calculated Molecular Weight | 43 kDa |
Observed Molecular Weight | 43 kDa |
GenBank Accession Number | BC002406 |
Gene Symbol | PDHA1 |
Gene ID (NCBI) | 5160 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
PDHA1(Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial) is also named as PHE1A.It is one of the 3 enzymes of the pyruvate dehydrogenase complex which is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA(PMID:7853374).It has 4 isoforms produced by alternative splicing.Defects in PDHA1 are a cause of pyruvate dehydrogenase E1-alpha deficiency (PDHAD) and X-linked Leigh syndrome (X-LS).