PDE9A Polyclonal antibody, PBS Only

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  IHC staining of human prostate cancer using 12648-1-AP (same clone as 12648-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 12648-1-AP (PDE9A Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 12648-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate cancer using 12648-1-AP (same clone as 12648-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 12648-1-AP (PDE9A Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 12648-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate cancer using 12648-1-AP (same clone as 12648-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer using 12648-1-AP (PDE9A antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 12648-1-PBS in a different storage buffer formulation.

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  IF Staining of A549 using 12648-1-AP (same clone as 12648-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using PDE9A antibody (12648-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 12648-1-PBS in a different storage buffer formulation.

PDE9A Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Cat No. 12648-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IF/ICC, Indirect ELISA

Synonyms

HSPDE9A2, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, EC:3.1.4.35

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Product Information

12648-1-PBS targets PDE9A in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: PDE9A fusion protein Ag3372
• Full Name: phosphodiesterase 9A
• Calculated Molecular Weight: 68 kDa
• Observed Molecular Weight: 50 kDa
• GenBank Accession Number: BC009047
• Gene Symbol: PDE9A
• Gene ID (NCBI): 5152
• RRID: AB_2161890
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O76083
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Cyclic nucleotide phosphodiesterases (PDEs), which hydrolyze the intracellular second messengers cAMP and cGMP to their corresponding monophosphates, play an important role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. PDE9A plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. This protein has 16 isoforms with the MW between 44 kDa and 65 kDa.