PDE6D Recombinant antibody, PBS Only

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  WB analysis using 83503-1-RR (same clone as 83503-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83503-1-RR (PDE6D antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83503-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HeLa using 83503-1-RR (same clone as 83503-1-PBS)

  WB result of PDE6D antibody (83503-1-RR; 1:4000; incubated at room temperature for 1.5 hours) with sh-Control and sh-PDE6D transfected HeLa cells. This data was developed using the same antibody clone with 83503-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

PDE6D Uni-rAb^TM Recombinant Antibody for WB, ELISA

Cat No. 83503-1-PBS

Clone No.230546H1

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

PDED, 230546H1

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Product Information

83503-1-PBS targets PDE6D in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: PDE6D fusion protein Ag29563
• Full Name: phosphodiesterase 6D, cGMP-specific, rod, delta
• Calculated Molecular Weight: 17 KDa
• Observed Molecular Weight: 14-17 kDa
• GenBank Accession Number: NM_002601
• Gene Symbol: PDE6D
• Gene ID (NCBI): 5147
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: O43924
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

PDE6D, also known as PDED, belongs to the PDE6D/unc-119 family. PDE6D is a ubiquitously expressed prenyl-binding protein. By binding to prenyl moieties, PDE6D mediates the shuttling of prenylated proteins between membranes. Thereby, it regulates the membrane association of Ras and Rap GTPases (PMID: 36672247). In addition, research has shown that PDE6D is overexpressed in liver cancer and correlated with tumor stages, grading, and ERK activation (PMID: 30901922). The calculated molecular weight of PDE6D is 17 kDa.