Product Information
66100-1-PBS targets PDCD4 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | PDCD4 fusion protein Ag19239 Predict reactive species |
Full Name | programmed cell death 4 (neoplastic transformation inhibitor) |
Calculated Molecular Weight | 469 aa, 52 kDa |
Observed Molecular Weight | 56 kDa |
GenBank Accession Number | BC026104 |
Gene Symbol | PDCD4 |
Gene ID (NCBI) | 27250 |
RRID | AB_2881499 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q53EL6 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation, progression and invasion. It was first identified as being differnetially upregulated during apoptosis. Pdcd4 interferes with the activity of the eukaryotic initiation factor (eIF) 4A by displacing the scaffold protein eIF4G from its binding to the RNA helicase eIF4A.