PCDH8 Recombinant antibody

PCDH8 Uni-rAb^TM Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

241362C6

Cat no : 84134-3-RR

Synonyms

Protocadherin-8, Arcadlin, 241362C6

---

Validation Data Gallery

• 

  WB analysis using 84134-3-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 84134-3-RR (PCDH8 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

---

Tested Applications

• Positive WB detected in: Neuro-2a cells, mouse brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 84134-3-RR is PCDH8 Fusion Protein expressed in E. coli.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: PCDH8 fusion protein Ag5090
• Full Name: protocadherin 8
• Calculated Molecular Weight: 1070 aa, 113 kDa
• Observed Molecular Weight: 104-120 kDa
• GenBank Accession Number: BC036025
• Gene Symbol: PCDH8
• Gene ID (NCBI): 5100
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Protocadherin-8 (PCDH8) is a member of the protocadherin family that belongs to the cadherin superfamily. Protocadherins are calcium-dependent adhesion proteins and have been implicated in neural cell-cell interactions. They are abundantly expressed in the central nervous system during embryonic development and in adulthood (PMID: 24214103). PCDH8 is a tumor suppressor involved in tumorigenesis.