PAK4/6/7 Polyclonal antibody, PBS Only

PAK4/6/7 Polyclonal Antibody for IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 12460-1-PBS

Synonyms

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Validation Data Gallery

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  IP experiment of mouse brain using 12460-1-AP (same clone as 12460-1-PBS)

  IP result of anti-PAK4/6/7 (IP:12460-1-AP, 4ug; Detection:12460-1-AP 1:300) with mouse brain tissue lysate 5200ug. This data was developed using the same antibody clone with 12460-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 12460-1-AP (same clone as 12460-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 12460-1-AP (PAK7 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12460-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 12460-1-AP (same clone as 12460-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 12460-1-AP (PAK7 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12460-1-PBS in a different storage buffer formulation.

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Product Information

12460-1-PBS targets PAK4/6/7 in IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: PAK4/6/7 fusion protein Ag3127
• Full Name: p21 protein (Cdc42/Rac)-activated kinase 7
• Calculated Molecular Weight: 719 aa, 81 kDa
• Observed Molecular Weight: 80 kDa
• GenBank Accession Number: BC024179
• Gene Symbol: PAK7
• Gene ID (NCBI): 57144
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

PAK7(p21-activated kinase 7) is also named as KIAA1264, PAK5 and belongs to the STE Ser/Thr protein kinase family. It plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. The antibody can recognize PAK4/6/7. PAK4/6/7 belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. It acts on a variety of targets.