P glycoprotein Recombinant antibody, PBS Only

P glycoprotein Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84295-3-PBS
Clone No.241512A1

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

ABCB1, 241512A1, EC:7.6.2.2, EC:7.6.2.1, ATP-dependent translocase ABCB1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

84295-3-PBS targets P glycoprotein in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein Predict reactive species
Full Name ATP-binding cassette, sub-family B (MDR/TAP), member 1
Calculated Molecular Weight 1280 aa, 142 kDa
Observed Molecular Weight 130-150 kDa
GenBank Accession NumberBC130424
Gene Symbol P glycoprotein
Gene ID (NCBI) 5243
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP08183
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.

Loading...