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  • Featured Product
  • KD/KO Validated

OTUD7B Monoclonal antibody, PBS Only

OTUD7B Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2C12D9

Cat no : 66276-1-PBS

Synonyms

CEZANNE, OTU domain containing 7B, OTUD7B, ZA20D1, Zinc finger protein Cezanne

Validation Data Gallery

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  • Western Blot (WB) analysis of Jurkat cells using OTUD7B Monoclonal antibody (66276-1-Ig)

    WB analysis of Jurkat using 66276-1-Ig (same clone as 66276-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 66276-1-Ig (OTUD7B Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66276-1-PBS in a different storage buffer formulation.

Product Information

66276-1-PBS targets OTUD7B in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen OTUD7B fusion protein Ag10513
Full Name OTU domain containing 7B
Calculated Molecular Weight427aa,48 kDa; 843aa,93 kDa
Observed Molecular Weight 92 kDa
GenBank Accession NumberBC020622
Gene Symbol OTUD7B
Gene ID (NCBI) 56957
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

OUTD7B is a member of the A20 family of the deubiquitinating cysteine proteases, which has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. It plays a key role in the negative feedback regulation of NF-κB signaling in response to multiple stimuli and has been described as central gatekeeper in inflammation and immunity.