OSTA Polyclonal antibody, PBS Only

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  WB analysis using 31330-1-AP (same clone as 31330-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31330-1-AP (SLC51A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31330-1-PBS in a different storage buffer formulation.

OSTA Polyclonal Antibody for WB, Indirect ELISA

Cat No. 31330-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

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Product Information

31330-1-PBS targets OSTA in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: OSTA fusion protein Ag34517
• Full Name: organic solute transporter alpha
• Calculated Molecular Weight: 340 aa, 38 kDa
• Observed Molecular Weight: 38 kDa
• GenBank Accession Number: NM_152672
• Gene Symbol: SLC51A
• Gene ID (NCBI): 200931
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q86UW1
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

SLC51A also known as OSTA, belongs to the OST-alpha family. SLC51A is an essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood (PubMed:16317684). SLC51A is located in basolateral plasma membrane and transported from the endoplasmic reticulum to the plasma membrane upon interacting with SLC51B. SLC51A is expressed with a high expression in kidney and intestine (PMID: 15563450). Mutations in SLC51A are associated with Cholestasis progressive familial intrahepatic 6(PMID: 31863603).