OSMR Monoclonal antibody

OSMR Monoclonal Antibody for ELISA
Cat No. 60071-1-Ig
Clone No.4B11D4

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

ELISA

Interleukin-31 receptor subunit beta, IL-31R-beta, IL-31RB, IL-31R subunit beta, IL-31 receptor subunit beta

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

60071-1-Ig targets OSMR in ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen OSMR fusion protein Ag1426 Predict reactive species
Full Name oncostatin M receptor
Calculated Molecular Weight 110 kDa
Observed Molecular Weight 120 kDa
GenBank Accession NumberBC010943
Gene Symbol OSMR
Gene ID (NCBI) 9180
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ99650
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Oncostatin M (OSM) is a member of interleukin-6 family cytokines that modulates proliferation and differentiation in numerous cells (PMID: 22982441). OSM signals via a receptor complex comprising gp130 and the OSMR (also called OSMRβ) (PMID: 8999038). OSMR is a single-pass membrane protein that belongs to the type I cytokine receptor family. OSMR mRNA is expressed at relatively high levels in all neural cells as well as fibroblast, epithelial and various tumor cell lines (PMID: 8999038). It has also been shown that OSMR associates with IL31RA to form the heterodimeric IL31 receptor (PMID: 15184896).

Protocols

Product Specific Protocols
WB protocol for OSMR antibody 60071-1-IgDownload protocol
Standard Protocols
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