Product Information
68241-1-PBS targets OPA3 in WB, Indirect ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | OPA3 fusion protein Ag8173 Predict reactive species |
Full Name | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
Calculated Molecular Weight | 179 aa, 20 kDa |
Observed Molecular Weight | 20 kDa |
GenBank Accession Number | BC005059 |
Gene Symbol | OPA3 |
Gene ID (NCBI) | 80207 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q9H6K4 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
The OPA3 cDNA encodes a deduced 179-amino acid protein. Northern blot analysis demonstrated a primary transcript of approximately 5.0 kb that was ubiquitously expressed, most prominently in skeletal muscle and kidney. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract.